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Mitral Regurgitation: Origins & Doppler Tricks

Mitral Regurgitation: Origins & Doppler Tricks

Aram K.'s avatar
Aram K.
Jun 10, 2025
∙ Paid
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The Echo Journal
The Echo Journal
Mitral Regurgitation: Origins & Doppler Tricks
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Who Discovered Heart Valves?

Between 310 and 250 BCE, Greek physician Erasistratus conducted some of the earliest anatomical studies of the human heart and brain. He emphasized mechanical principles over traditional physiological theories and is credited with identifying the heart’s four valves and their role in ensuring unidirectional blood flow.

He also became well-known for diagnosing the emotional turmoil of the future King Antiochus and recommending marriage as a way to ease his distress. More broadly, his focus on the mechanical function of the heart laid the groundwork for future pioneers studying cardiac valves.

What Is Mitral Regurgitation?

Mitral valve regurgitation (MR) is the most common form of heart valve disease. It occurs when the mitral valve leaflets fail to close properly, allowing blood to flow backward into the left atrium. According to recent studies published by the National Library of Medicine, MR affects approximately 2% of the global population.

2 Types of Mitral Regurgitation

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